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Pharmacology Final

Number of questions: 14

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1) The bactericidal antibiotic that interferes with bacterial cell-wall synthesis and that may cause "red man syndrome" if injected too rapidly is
  1. piperacillin
  2. vancomycin
  3. gentamicin
  4. clindamycin
Answers are locked. Please click here to buy them. 2) The antibiotic whose adverse effects include heartburn, photosensitivity, and possible depression of bone growth in young children is
  1. erythromycin
  2. tetracycline
  3. gentamicin
  4. clindamycin
Answers are locked. Please click here to buy them. 3) The main pharmacokinetic feature of aminoglycosides is that they are
  1. lipid soluble
  2. well absorbed orally
  3. poorly absorbed from the GI tract and excreted mostly unchanged in the urine if injected
  4. devoid of serious adverse effects
Answers are locked. Please click here to buy them. 4) Griseofulvin is useful in dermatophytic infections because it
  1. binds to keratin
  2. is fungicidal
  3. forms ergosterol in hair and nails
  4. incorporates itself into fungal RNA
Answers are locked. Please click here to buy them. 5) Which antifungal drug is matched with its correct mechanism of action?
  1. echinocandins inhibit polysaccharide (glucan) synthesis in the cell wall
  2. flucytosine binds to the cell membrane
  3. ticonazole is an antimetabolite for fungal RNA
  4. amphotericin B binds to a cytochrome P450-dependent enzyme
Answers are locked. Please click here to buy them. 6) The mechanisms of action for antiviral medications include
  1. binding to ergosterol
  2. inhibiting cell mitosis
  3. inhibiting neuraminidase
  4. facilitating viral fusion to the host cell
Answers are locked. Please click here to buy them. 7) The antimetabolite that blocks DNA synthesis by interfering with folic acid is
  1. mercaptopurine
  2. fluorouracil
  3. methotrexate
  4. cytarabine
Answers are locked. Please click here to buy them. 8) The drug that binds to mitotic tubules to cause metaphase arrest is
  1. doxorubicin
  2. asparaginase
  3. etoposide
  4. vincristine
Answers are locked. Please click here to buy them. 9) Enzyme inhibition of aromatase is the mechanism of action of
  1. tamoxifen
  2. anastrozole
  3. leuprolide
  4. goserelin
Answers are locked. Please click here to buy them. 10) The monoclonal antibody that inhibits vascular endothelial growth factor (VEGF) and new blood vessel formation is
  1. imatinib
  2. trastuzumab
  3. bevacizumab
  4. gefitinib
Answers are locked. Please click here to buy them. 11) Which of the following is true of chemotherapy?
  1. one of the early goals of chemotherapy is remission
  2. antineoplastic drugs only attack cancerous cells
  3. drug resistance is increased with combination therapy
  4. it is the primary form of treatment for solid tumors
Answers are locked. Please click here to buy them. 12) Select the correct statements for alkylating drugs.
  1. decrease cells' ability to synthesize proteins
  2. are cell-cycle nonspecific
  3. bind irreversibly with nucleic acids and are cell-cycle nonspecific
  4. all statements are true
Answers are locked. Please click here to buy them. 13) The mechanisms of actions for the antimetabolites include
  1. blocking DNA synthesis
  2. forming abnormal nucleotides
  3. preventing DNA replication and forming abnormal nucleotides
  4. all of these
Answers are locked. Please click here to buy them. 14) Select the correct statements about the plant extract treatments for cancer.
  1. they can bind to microtubules
  2. they induce enzymes
  3. they increase DNA strand breakage
  4. they can bind to microtubules, and they increase DNA strand breakage
Answers are locked. Please click here to buy them.

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