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Blood practice questions

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Blood practice questions

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1) What is a neutrophil?
  1. A bacteria that prefers a neutral (pH 7) environment
  2. A type of coagulation factor in the blood
  3. A type of white blood cell
    A neutrophil is a type of white blood cell. It is the most common type of white blood cell in the body. Neutrophils engulf and destroy microbes through a process called phagocytosis.
  4. An atom with more neutrons than electrons
2) Which term means a low white blood cell count?
  1. Leukocytosis
    Leukocytosis is an abnormally high level of white blood cells.
  2. Leukodystrophy
    Leukodystrophies are disorders affecting the white matter of the brain.
  3. Leukopenia
    Leukopenia is a low white blood cell count.
  4. Leukoplakia
    Leukoplakia is white patches in the mouth.
3) Which coagulation pathway is also known as the contact activation pathway?
  1. Common pathway
  2. Extrinsic pathway
  3. Intrinsic pathway
    The intrinsic pathway is also known as the contact activation pathway, because it is triggered by contact with certain surfaces, such as collagen.
  4. Tissue factor pathway
    Tissue factor pathway is another name for the extrinsic pathway. It is called the tissue factor pathway because it is activated by tissue factor, a protein released from damaged tissues.
4) What does angiotensin-converting enzyme convert angiotensin I to?
  1. Aldosterone
  2. Angiotensin II
    Angiotensin I is a biologically inactive precursor to angiotensin II. The angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II. Angiotensin II exerts various effects on the body, including stimulating the release of vasopressin (antidiuretic hormone).
  3. Angiotensin III
  4. Renin
5) What are the three major groups of plasma proteins?
  1. Albumin, fibrinogen, and globulin
    The major groups of proteins in plasma are albumin, fibrinogen, and globulin. Albumin is the most abundant plasma protein. It helps maintain osmotic pressure, transports substances, and regulates blood volume. Fibrinogen is a clotting factor. It converts into fibrin, forming a clot to stop bleeding. Globulins are a diverse group of proteins. There are three types of globulins: alpha, beta, and gamma. Alpha globulins transport lipids, fatty acids, and certain vitamins. Beta globulins transport iron and other substances. Gamma globulins, also known as antibodies, are used in immune responses.
  2. Albumin, globulin, and hemoglobin
  3. Fibrin, globulin, and albumin
  4. Insulin, glucagon, and hemoglobin
6) In the process of hemostasis, which phase involves the intrinsic and extrinsic pathways?
  1. Clot formation phase
  2. Coagulation phase
    Hemostasis can be divided into four stages:
    1. Vascular phase: Constriction of the blood vessel
    2. Platelet phase: Formation of a temporary “platelet plug"
    3. Coagulation phase: Activation of the coagulation cascade
    4. Clot formation: Formation of the “fibrin plug” or the final clot
    The coagulation phase is where most of the clotting factor activity happens. The intrinsic and extrinsic pathways converge here, involving a complex cascade of clotting factor activations that ultimately lead to clot formation.
  3. Platelet phase
  4. Vascular phase
7) Which factor do damaged blood vessels release to activate the extrinsic pathway of coagulation?
  1. Factor VII
  2. Prothrombin
  3. Thrombin
  4. Tissue factor
    Damage to blood vessels releases tissue factor (also known as factor III). It binds with factor VII and calcium to form a complex that activates the extrinsic pathway of the coagulation cascade.
8) What is the first step of hemostasis?
  1. Blood coagulation
  2. Temporary blockage of a break by a platelet plug
  3. Vasoconstriction
    Hemostasis has three major steps:
    1. vasoconstriction
    2. temporary blockage of a break by a platelet plug
    3. blood coagulation
  4. Vasodilation
9) In hemostasis, which molecule polymerises to become the blood clot?
  1. Factor X
  2. Fibrin
    During hemostasis, fibrin monomers polymerize (link together) to form long chains. These chains create a mesh that traps platelets and red blood cells, forming a blood clot that seals the wound.
  3. Plasmin
  4. Thrombin
10) Which enzyme converts fibrinogen to fibrin?
  1. Renin
  2. Secretin
  3. Serotonin
  4. Thrombin
    Factor IIa (also known as thrombin) cleaves fibrinogen into the fibrin monomers that form a fibrin clot.
11) What causes oncotic pressure in blood?
  1. Proteins in the blood
    Oncotic pressure is the osmotic pressure exerted by large molecules in the blood, mainly albumin.
  2. Proteins in the interstitial fluid
  3. Sodium and chloride ions in the blood
  4. The water component of the blood
12) Which of these is a formed element of blood?
  1. Electrolytes
  2. Fibrinogen
  3. Plasma proteins
  4. White blood cells
    Formed elements are cells and cell fragments suspended in the plasma. The three classes of formed elements are red blood cells, white blood cells, and platelets.
13) What are formed elements?
  1. Blood cells
    The formed elements are the cells in the blood. The three classes of formed elements are red blood cells, white blood cells, and platelets.
  2. Clotting factors
  3. Plasma proteins
  4. Serum antibodies
14) What does amylase break down?
  1. Fat
  2. Protein
  3. Starch
    Amylase is an enzyme that breaks down starch into disaccharides and trisaccharides. Other enzymes then convert these into glucose.
  4. Sugars
15) Which of these cells is NOT found in blood?
  1. Basophils
  2. Erythrocytes
  3. Leukocytes
  4. Osteocytes
    Osteocytes are found in bone tissue.
16) What are the two most common types of white blood cells?
  1. Monocytes and eosinophils
  2. Monocytes and lymphocytes
  3. Neutrophils and basophils
  4. Neutrophils and lymphocytes
    Neutrophils and lymphocytes together make up around 92% of all white blood cells in adults.
17) Which blood cell has a multi-lobed nucleus and inconspicuous cytoplasmic granules, and is also the most common type of blood cell after red blood cells?
  1. Basophil
  2. Eosinophil
  3. Lymphocyte
  4. Neutrophil
    Neutrophils are the most common type of white blood cell in normal blood. They are easy to recognize on a blood smear because they usually have a segmented, multi-lobed nucleus, often with 3–5 lobes. Their cytoplasmic granules are usually pale and hard to see, so they may be described as inconspicuous.
18) Which blood cells protect the body from pathogens and foreign cells?
  1. Erythrocytes
  2. Hemoglobin
  3. Leukocytes
    Leukocytes, also known as white blood cells, protect the body from infection.
  4. Platelets
19) Serum and plasma both contain:
  1. albumin
    Plasma is the liquid part of blood. It contains plasma proteins (albumin, globulin, and fibrinogen), clotting factors, electrolytes, antibodies, antigens, and hormones. Serum is the liquid portion that is left over when blood clots. It is similar to plasma but lacks fibrinogen and some clotting factors, which are used during clotting.
  2. fibrinogen
    Fibrinogen is found in plasma. Serum lacks fibrinogen because it is used up in the clotting process.
  3. platelets
    Plasma and serum do not contain platelets.
  4. red blood cells
    Plasma and serum do not contain red blood cells.
20) What is another name for red blood cells?
  1. Eosinophils
  2. Erythrocytes
    The scientific name for red blood cells is erythrocytes. The word comes from erythro, meaning 'red', and cyte, meaning 'cell'.
  3. Monocytes
  4. Thrombocytes
21) What is the main task of red blood cells?
  1. To ensure hemostasis
  2. To provide immunity
  3. To stop bleeding by forming a clot over injuries
  4. To transport oxygen and carbon dioxide
    Red blood cells have two tasks: carrying oxygen and carrying carbon dioxide. They carry oxygen from the lungs to the body's tissues to ensure the tissues have enough oxygen. At the same time, they carry carbon dioxide to the lungs for removal from the body.
22) What are red blood cells mainly composed of?
  1. Albumin
  2. Globulins
  3. Hemoglobin
    Red blood cells are mostly made of hemoglobin (about 95% of their solid material is hemoglobin). They have no nucleus or organelles, which gives them extra space to carry hemoglobin.
  4. Mitochondria
23) What are the two main types of lymphocytes?
  1. B cells and T cells
    Lymphocytes are a type of immune cell. The two main types of lymphocytes are B cells and T cells. B cells make antibodies while T cells help kill tumor cells and control immune responses.
  2. Cytotoxic cells and helper cells
    Cytotoxic cells and helper cells are different functions of T cells.
  3. Granulocytes and agranulocytes
  4. Macrophages and thrombocytes
24) Which of these is a phagocyte?
  1. B cell
  2. Basophil
  3. Neutrophil
    Phagocytes are a type of white blood cell that ingest and destroy pathogens. They include monocytes, macrophages, neutrophils, and dendritic cells. White blood cells that are not phagocytes include lymphocytes (B cells, T cells, and natural killer cells), basophils, and eosinophils.
  4. T cell
25) Identify the true statement about neutrophils.
  1. Neutrophils are part of the adaptive immune system
  2. Neutrophils are part of the innate immune system
    Neutrophils are part of the innate immune system, which is the body's first line of defense against pathogens. Neutrophils capture and destroy invading microorganisms, through methods such as phagocytosis.
  3. Neutrophils contain hemoglobin
  4. Neutrophils do not have a nucleus
26) Which of these is NOT a type of white blood cell?
  1. Basophil
  2. Eosinophil
  3. Erythrocyte
    Erythrocytes are red blood cells, not white blood cells.
  4. Neutrophil
27) Which of these is a macrophage?
  1. Basophil
  2. Kupffer cell
    Macrophages are a type of white blood cell that engulf and digest pathogens. Kupffer cells are macrophages found in the liver. Other macrophages include alveolar macrophages (found in the lungs), microglia (found in the central nervous system), and histiocytes (found in connective tissue).
  3. Megakaryocyte
  4. T cell
28) Which is the least common white blood cell?
  1. Basophil
    Basophils are the rarest type of white blood cell, making up only 1% of the white blood cells in the blood.
  2. Lymphocyte
  3. Neutrophil
  4. Thrombocyte
29) What is the role of platelets in hemostasis?
  1. Converting prothrombin to thrombin
  2. Forming a plug at sites of bleeding
    Platelets are blood cells that help in clotting by forming a plug in the holes of damaged blood vessels.
  3. Producing clotting factors
  4. Transporting oxygen
30) Lipase breaks down:
  1. enzymes
  2. fats
    Lipase is an enzyme that breaks down fats into fatty acids and glycerol during digestion.
  3. proteins
  4. red blood cells
31) Vitamin K:
  1. converts prothrombin to thrombin
    Prothrombinase converts prothrombin to thrombin, not vitamin K.
  2. destroys fibrin which allows a clot to dissolve gradually
    The enzyme plasmin breaks down fibrin and dissolves clots, not vitamin K.
  3. is essential for the liver's production of prothrombin
    Vitamin K is essential for the liver's production of prothrombin as well as several other proteins involved in blood clotting.
  4. is water soluble
    Vitamin K is fat-soluble, not water-soluble.
32) What is the preferred source of DNA for DNA testing?
  1. Plasma proteins
  2. Red blood cells
  3. Sweat
  4. White blood cells
    White blood cells are the preferred source of DNA samples. Red blood cells and plasma proteins do not contain DNA and therefore cannot be used for DNA testing. Sweat can contain DNA because it can contain shed cells, but white blood cells is the best answer.
33) The absence of which antigen makes red blood cells resistant to Plasmodium vivax malaria?
  1. Duffy
    Red blood cells lacking the Duffy antigen are relatively resistant to infection by Plasmodium vivax, the parasite that causes Plasmodium vivax malaria. The Duffy antigen is absent from the red blood cells of 90% of sub-Saharan Africans, conferring malaria resistance in this population.
  2. Kidd
  3. Lewis
  4. Rhesus
34) Which red blood cell types can usually be transfused to a type B− patient?
  1. B− and AB−
  2. B− and A−
  3. B− and O−
    People with type B blood cannot receive any blood that has A antigens (i.e. type A or AB blood), because their immune system makes anti-A antibodies. If they receive blood with A antigens, it can cause a dangerous hemolytic reaction. Furthermore, Rh-negative patients are usually given Rh-negative red blood cells to avoid exposure to the D antigen and possible anti-D formation. So, a person with B− blood should receive B− or O− blood, which do not have A or D antigens.
  4. O− and O+
35) A person's blood group is determined by:
  1. the antibodies circulating in their blood
  2. the antibodies on the surface of their red blood cells
  3. the antigens circulating in their blood
  4. the antigens on the surface of their red blood cells
    Blood group classification is based on the presence or absence of antigens on the surface of red blood cells. Blood group A has A antigens on the red blood cells, blood group B has B antigens on the red blood cells, blood group AB has both A and B antigens on the red blood cells, and blood group O has neither the A nor the B antigens on the red blood cells.
36) What does "Rhesus positive" mean?
  1. The antibodies in a pregnant woman's blood are destroying her baby's blood cells
  2. The person has a deficiency of Factor VIII, resulting in hemophilia
  3. The person has the D antigen on the surface of their red blood cells
    "Rhesus positive" means a person has the D antigen on the surface of their red blood cells. This antigen is part of the Rhesus (Rh) blood group system, which is significant for blood transfusions and pregnancy.
  4. The person has the rhesus antibody in their blood
37) A person who is blood group B has:
  1. A antigens and anti-A antibodies
  2. A antigens and anti-B antibodies
  3. B antigens and anti-A antibodies
    Blood group B individuals have B antigens on their red blood cells and anti-A antibodies in their bloodstream.
  4. B antigens and anti-B antibodies
38) Which blood type can receive red blood cells from an AB donor?
  1. Type A
  2. Type AB
    People with type AB blood can only donate red blood cells to other people with type AB blood. AB red blood cells have both A and B antigens, and recipients with type A, B, or O blood have anti-A and/or anti-B antibodies that attack these cells and cause a hemolytic transfusion reaction.
  3. Type B
  4. Type O
39) Which blood type is the universal recipient?
  1. A+
  2. AB+
    People with AB+ blood are often called universal red blood cell recipients. Their plasma does not contain anti-A or anti-B antibodies, so they can receive red blood cells from any ABO group. Because they are RhD positive, they can also receive RhD-positive or RhD-negative red blood cells without forming anti-D.
  3. B+
  4. O+
40) Which proteins on the surface of red blood cells determine a person's ABO blood type?
  1. Agglutinins
  2. Antibodies
  3. Antigens
    The ABO blood group system is based on two antigens on red blood cells: the A antigen and the B antigen. The presence or absence of these antigens determines a person's ABO blood type.
  4. Immunoglobulins
41) What is present on type A red blood cells?
  1. A antigens
    People with type A blood have A antigens on their red blood cells.
  2. B antigens
  3. Anti-A antibodies
  4. Anti-B antibodies
42) A person with the A antigen on their red blood cells also has what in their blood?
  1. Anti-A antibodies
  2. Anti-B antibodies
    In the ABO blood group system, people make antibodies against the antigens they do not have on their red blood cells. For example, a person with A antigens but no B antigens produces anti-B antibodies.
  3. Both anti-A and anti-B antibodies
  4. B antigens

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