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CAMLPR Histology Practice Questions

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About the CAMLPR Histology exam

The CAMLPR Histology exam is one of the single-field exams administered by the Canadian Alliance of Medical Laboratory Professionals Regulators (CAMLPR). The other single-field exams are Clinical Chemistry, Hematology, Clinical Microbiology, Transfusion Medicine, Cytogenetics, Molecular Diagnostics, and Cytology.

The histology exam tests your knowledge of how tissue specimens are prepared, examined, and interpreted. This includes tissue fixation, processing, embedding, sectioning, staining, special stains, immunohistochemistry, quality control, microscopy, and the use of manual and automated techniques to support disease diagnosis and patient care.

About these practice questions

These practice questions will help prepare you for the CAMLPR Histology exam.

This page contains 300 practice questions divided into the eight sections of the exam: 1. Specimen Collection, 2. Preparation and Testing, 3. Evaluation and Interpretation, 4. Reporting and Communication, 5. Equipment and Resources, 6. Safety, 7. Professionalism, and 8. Quality Assurance.

All questions have been carefully designed to mimic the questions on the real exam, to help you prepare and get a passing grade.

Sections

  1. Specimen Collection
  2. Preparation and Testing
  3. Evaluation and Interpretation
  4. Reporting and Communication
  5. Equipment and Resources
  6. Safety
  7. Professionalism
  8. Quality Assurance

Section 1: Specimen Collection

1.1) What is the term for the time between tissue excision and placement of the tissue in fixative?
  1. Autolysis transit time
  2. Clearing time
  3. Cold ischemia time
  4. Latency time
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1.2) A lung and liver specimen are collected from the same patient during the same procedure. How should they be submitted?
  1. In the same container with a single requisition form
  2. In the same container with separate requisition forms
  3. In separate containers with a single requisition form
  4. In separate containers with separate requisition forms
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1.3) A breast biopsy container is labelled "left breast", but the request form says "right breast". What should the laboratory do?
  1. Contact the patient to confirm the correct side
  2. Contact the surgical department
  3. Discard the specimen and request a new one
  4. Process the specimen, but add a note in the file
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1.4) A fresh, unfixed tissue specimen arrives for flow cytometry, but the lab is closed for the night. Where should the specimen be stored?
  1. In formalin
  2. In the freezer
  3. In the incubator
  4. In the refrigerator
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1.5) When a clinician submits a gynecologic specimen for histological testing, which extra information should the clinician provide to the histology laboratory?
  1. Date of last mammogram
  2. Date of last menstrual period
  3. Patient's body mass index
  4. Patient’s blood type
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1.6) A liver specimen for quantitative iron must be transported in:
  1. Michel's transport medium
  2. a metal-free container
  3. a tube with zinc-formalin fixative
  4. an amber glass vial
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1.7) If a fixative cannot be added promptly, tissue specimens should be wrapped in a _______________ and refrigerated.
  1. dry sterile foil wrap
  2. moist saline gauze
  3. plastic specimen bag
  4. water-soaked paper towel
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1.8) A surgical team asks whether a fresh specimen for frozen section can wait for 3 hours before being sent to histology. What is the best response?
  1. Yes, fresh specimens are stable for several hours
  2. Yes, if stored in distilled water
  3. Yes, if stored in formalin
  4. No, fresh specimens should be sent promptly
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1.9) A histology specimen arrives in the laboratory. The specimen is labelled correctly, but the requisition is missing. What is the best action?
  1. Discard the specimen and request another
  2. Obtain the missing request information
  3. Return the specimen to the surgical department
  4. Send the specimen to a reference laboratory
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1.10) After a surgical biopsy specimen is removed from a patient, what fluid is it usually placed in?
  1. 0.9% saline
  2. 10% neutral-buffered formalin
  3. 70% denatured ethanol
  4. PVA
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1.11) Which of these specimens should be transported without a fixative?
  1. Colon resection for adenocarcinoma staging
  2. Gallbladder for cholecystitis assessment
  3. Lymph node for flow cytometry
  4. Skin excision for carcinoma evaluation
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1.12) When submitting a tissue specimen for routine histology, what times should the clinician provide to the laboratory?
  1. Admission time and discharge time
  2. Embedding time and sectioning time
  3. Excision time and fixation start time
  4. Staining time and coverslipping time
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1.13) Specimens for intraoperative consultation should be submitted:
  1. in PreservCyt solution
  2. in RPMI media
  3. in formalin
  4. without a fixative
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1.14) A specimen arrives in the laboratory with a requisition, but there is no patient label on the container. What should the technologist do?
  1. Ask the staff member who took the specimen to confirm which patient the specimen belongs to
  2. Label the container using the information from the requisition
  3. Reject the specimen
  4. Report the specimen as a confidentiality breach
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1.15) A histology specimen is marked STAT, but its label does not match the request form. What should the MLT do?
  1. Ask the operating room to resolve the mismatch
  2. Change the label to match the request form
  3. Change the request form to match the label
  4. Process it immediately
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1.16) Tissues should be placed in fixative within _________ after removal from the body.
  1. 2 minutes
  2. 10 minutes
  3. 30 minutes
  4. 1 hour
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1.17) When transporting tissue specimens in cold weather, how much alcohol should be added to the formalin to prevent the tissue from developing freeze artifacts?
  1. 1 part alcohol to 3 parts formalin
  2. 1 part alcohol to 5 parts formalin
  3. 1 part alcohol to 7 parts formalin
  4. 1 part alcohol to 9 parts formalin
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1.18) Specimens should be placed in a fixative that is ______ times greater than the volume of the tissue.
  1. 10–20
  2. 20–30
  3. 30–40
  4. 40–50
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1.19) Approximately how quickly does formalin penetrate tissue?
  1. 1 mm/hour
  2. 2 mm/hour
  3. 5 mm/hour
  4. 10 mm/hour
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Section 2: Preparation and Testing

Section 3: Evaluation and Interpretation

Section 4: Reporting and Communication

Section 5: Equipment and Resources

Section 6: Safety

Section 7: Professionalism

Section 8: Quality Assurance

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